AG® 11 A8 Resin

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Overview

Specifications of AG® 11 A8 Resin
Resin Crosslinkage Approx.
MW Exclusion
Operating Stability/pH Range Min. Wet Capacity (meq/ml) Nominal Density (g/ml) Ionic Forms
Type: Ion retardation 8% 1,000 0–14/0–14 0.7 0.7 Self-adsorbed
Functional group:
R-CH2N+(CH3)3 and
R-CH2COO-
Matrix: Acrylic acid within
styrene divinylbenzene
Applications: Contains paired anions and cation exchange sites. Selectively retards ionic substances. Useful for desalting nonionic substances and for ion removal from ionic substances; for example, removal of SDS from proteins and inorganic salts from amino acids.
Analytical Grade Resin Selection Guide
Analytical Grade Resin Selection Guide
Relative Selectivity of Various Counterions on Selected AG Resins
AG 50W-X8 Resin
AG 1-X8 Resin
Counterion
Relative Selectivity
Counterion
Relative Selectivity
H+
1.0
OH–
1.0
Li+
0.85
F–
1.6
Na+
1.5
Propionate
2.6
NH4+
1.95
Acetate
3.2
Mn2+
2.35
Formate
4.6
K+
2.5
HPO4
5.0
Mg2+
2.5
IO3
5.5
Fe2+
2.55
HCO3
6.0
Rb+
2.6
Cl–
22
Cs+
2.7
NO2
24
Zn2+
2.7
BrO3
27
Co2+
2.8
HSO3
27
Cu2+
2.9
CN–
28
Cd2+
2.95
Br–
50
Ni2+
3.0
NO3
65
Ca2+
3.9
ClO3
74
Sr2+
4.95
HSO4
85
Cu+
5.3
Phenate
110
Hg2+
7.2
I–
175
Pb2+
7.5
Citrate
220
Ag+
7.6
Salicylate
450
Ba2+
8.7
Benzenesulfonate
500
Order of Selectivity for Monovalent and Divalent Ions
Anions I > phenolate > HSO4 > CIO3 > NO3 > Br > CN > HSO3 > NO2 > Cl > HCO3 > IO3 > H2COO > Ac > OH > F
Cations H > Ag > Rb > Cs > K > NH4 > Na > Li > Zn > Cu > Ni > Co

The strength with which a salt is absorbed, and therefore the degree to which it is retarded and separated from organic substances, is proportional to the strength with which one or both of its constituent ions is absorbed.

Selecting Cation or Anion Exchange Support

Separation strategy for amphoteric molecules. If the molecule is stable at a pH above its pl, an anion exchange support is used. If the molecule is stable at a pH below its pl, a cation exchange support is used.

Stability of Selected Analytical Grade Resins to Various Treatments
Resin
Heat*
Solvents (Alcohols,
Hydrocarbons, etc.)
Oxidation
Reduction
AG 1 OH- form, fair to 50°C
Cl- and other forms,
good to 150°C
Very good Slowly dissolves in
hot 15% HNO3
or concentrated H2O2
Good**
AG 2 OH- form, fair to 30°C
Cl- form, good to 150°C
Very good Slowly dissolves in
hot 15% HNO3
Good**
AG 50W Good to 150°C Very good Slowly dissolves in
hot 15% HNO3
Very good
AG 4-X4 Good to 60°C Good Good Unknown
AG 501-X8 Good to 50°C Very good Slowly dissolves in
hot 15% HNO3
or concentrated H2O2
Good**
AG 11 A8 Good to 100°C Good Slowly dissolves in
hot 15% HNO3
or concentrated H2O2
Good
Bio-Rex 5 Good to 60°C Good Good Excellent
Bio-Rex 70 Good to 100°C Good Good Good
Bio-Rex MSZ 501(D) Good to 50°C Very good Slowly dissolves in
hot 15% HNO3
or concentrated H2O2
Good**
Chelex 100 Good to 75°C Good Breaks down in strong
oxidizing agents
Unknown
* All anion resins may be autoclaved except the CH- form; all cation exchange resins may be autoclaved.
** AG 1, AG 2, AG 501, and Bio-Rex MSZ 501 (D) resins will slowly break down in the presence of sulfur-containing reducing agents.
AG Resin Equivalent Diameters
Analytical Grade Resin Wet Mesh and Equivalent Diameters
Wet mesh (U.S. Standards) 16 20 40 50 80 100 140 200 270 325 400
Diameter, µm 1,180 850 425 300 180 150 106 75 53 45 38


AG 11 A8 ion retardation resin is extremely useful for chromatographic desalting, or removing acid from non-ionic molecules. It separates salts from organic materials by absorbing both anions and cations in equivalent amounts while allowing the organic compounds to pass through. Both analytical and biotechnology grades of AG 11 A8 resin are available. Biotechnology grade AG 11 A8 resin is certified to contain less than 100 microorganisms per gram of resin.

The AG 11 A8 resin selectively retards ionic substances, so it can be used for desalting non-ionic solutions and for separating ions from ionic substances. Organic molecules, even ionic species such as acidic and basic amino acids, are usually not absorbed by AG 11 A8 resin, whereas inorganic ions are absorbed, thus achieving the separation.

AG 11 A8 resin is made by polymerization of acrylic acid moieties inside the AG 1-X8 resin, which produces a spherical resin bead containing paired anion and cation exchange sites. The result is a styrene divinylbenzene crosslinked, rigid polymer lattice with attached quaternary ammonium groups (strongly basic anion exchange groups), within which weaves a trapped, linear, relatively flexible acrylic polymer having carboxyl groups (weakly acidic cation exchange groups). Each resin bead is a molecular mixture of a cation and anion exchanger.

Larger volumes and special packaging for industrial applications are available on request.

AG 11 A8 Resin

142-7834
500 g, analytical grade ion exchange resin, self-adsorbed form, 8% crosslinkage, 50–100 dry mesh size, 180–425 µm wet bead size, ~1,000 MW limit

List Price:   $522.00
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AG 11 A8 Resin

143-7834
100 g, biotechnology grade ion exchange resin, self-adsorbed form, 8% crosslinkage, 50–100 dry mesh size, 180–425 µm wet bead size, ~1,000 MW limit

List Price:   $374.00
Your Price:   Log in
Quantity:   Add to cart
Add to Hot List   Add to Quote