AG 11 A8 ion retardation resin is extremely useful for chromatographic desalting, or removing acid from non-ionic molecules. It separates salts from organic materials by absorbing both anions and cations in equivalent amounts while allowing the organic compounds to pass through. Both analytical and biotechnology grades of AG 11 A8 resin are available. Biotechnology grade AG 11 A8 resin is certified to contain less than 100 microorganisms per gram of resin.
The AG 11 A8 resin selectively retards ionic substances, so it can be used for desalting non-ionic solutions and for separating ions from ionic substances. Organic molecules, even ionic species such as acidic and basic amino acids, are usually not absorbed by AG 11 A8 resin, whereas inorganic ions are absorbed, thus achieving the separation.
AG 11 A8 resin is made by polymerization of acrylic acid moieties inside the AG 1-X8 resin, which produces a spherical resin bead containing paired anion and cation exchange sites. The result is a styrene divinylbenzene crosslinked, rigid polymer lattice with attached quaternary ammonium groups (strongly basic anion exchange groups), within which weaves a trapped, linear, relatively flexible acrylic polymer having carboxyl groups (weakly acidic cation exchange groups). Each resin bead is a molecular mixture of a cation and anion exchanger.
Larger volumes and special packaging for industrial applications are available on request.