PrimePCR™ Template for SYBR® Green Assay: HMBS, Human

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PrimePCR Primer Assays for Real-Time PCR synthetic positive control DNA template tube

Gene-specific template designed to give a positive real-time PCR result when used with the corresponding gene assay.

This template is intended for use with the real-time PCR SYBR Green assay with the following Unique Assay ID: qHsaCID0038839

Reaction:  200 x 20 µl reactions desalted
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Gene Information

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   HMBS
Gene Name:   hydroxymethylbilane synthase
Aliases:   PBG-D, PBGD, PORC, UPS
Ensembl:   ENSG00000256269
Entrez:   3145
UniGene:   Hs.82609
RefSeq:   NC_000011.9 NG_008093.1 NT_033899.8
Chromosome Mapping   11q23.3

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