PrimePCR™ Template for Probe Assay: G6PD, Human

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PrimePCR Primer Assays for Real-Time PCR synthetic positive control DNA template tube

Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.

This template is intended for use with the real-time PCR probe assay with the following Unique Assay ID: qHsaCEP0025798

Reaction:  200 x 20 µl reactions desalted
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Gene Information

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD mostly produced from missense mutations have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice acute hemolysis or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   G6PD
Gene Name:   glucose-6-phosphate dehydrogenase
Aliases:   G6PD1
Ensembl:   ENSG00000160211
Entrez:   2539
UniGene:   Hs.461047
RefSeq:   NC_000023.10 NG_009015.1 NG_009896.1 NT_167198.1
Chromosome Mapping   Xq28

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