Gene:  WWOX, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation transcription and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis ovary and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis suggesting a similar important role in apoptosis for the human protein. In addition there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: WWOX, Human
WW domain containing oxidoreductase

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038777
Info:   Same primer pair as used in probe assay qHsaCEP0041499
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PrimePCR™ Probe Assay: WWOX, Human
WW domain containing oxidoreductase

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0041499
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: WWOX, Human
WW domain containing oxidoreductase

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5006683
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038777; exonic
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PrimePCR™ ddPCR™ Expression Probe Assay: WWOX, Human
WW domain containing oxidoreductase

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5031678
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041499; exonic
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Expression Probe Assay: WWOX, Human
WW domain containing oxidoreductase

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5031679
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0041499; exonic
 
Fluorophore:   HEX
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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