Gene:  UMOD, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes uromodulin the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia gout and progressive renal failure. While several transcript variants may exist for this gene the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: UMOD, Human
uromodulin

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021604
Info:   Same primer pair as used in probe assay qHsaCIP0033108
List Price:    $125.00
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PrimePCR™ Probe Assay: UMOD, Human
uromodulin

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0033108
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: UMOD, Human
uromodulin

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5024079
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0021604; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: UMOD, Human
uromodulin

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057590
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033108; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: UMOD, Human
uromodulin

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5057591
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0033108; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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