Gene:  UCP3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.[provided by RefSeq Nov 2008]

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PrimePCR™ SYBR® Green Assay: UCP3, Human
uncoupling protein 3 (mitochondrial, proton carrier)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038190
Info:   Same primer pair as used in probe assay qHsaCEP0040912
List Price:    $125.00
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PrimePCR™ Probe Assay: UCP3, Human
uncoupling protein 3 (mitochondrial, proton carrier)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040912
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: UCP3, Human
uncoupling protein 3 (mitochondrial, proton carrier)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5006438
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038190; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: UCP3, Human
uncoupling protein 3 (mitochondrial, proton carrier)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5031188
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040912; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: UCP3, Human
uncoupling protein 3 (mitochondrial, proton carrier)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5031189
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040912; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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