Gene:  Trem2, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is part of the immunoglobulin and lectin-like superfamily and functions as part of the innate immune system. This gene forms part of a cluster of genes on mouse chromosome 17 thought to be involved in innate immunity. This protein associates with the adaptor protein Dap-12 and recruits several factors such as kinases and phospholipase C-gamma to form a receptor signaling complex that activates myeloid cells including dendritic cells and microglia. In humans homozygous loss-of-function mutations in this gene cause Nasu-Hakola disease and mutations in this gene may be risk factors to the development of Alzheimer's disease. In mouse mutations of this gene serve as a pathophysiological model for polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (Nasu-Hakola disease) and for inflammatory bowel disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq Jan 2013]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: Trem2, Mouse
Triggering receptor expressed on myeloid cells 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCED0046145
Info:   Recommended - best efficiency; Same primer pair as used in probe assay qMmuCEP0054571
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: Trem2, Mouse
Triggering receptor expressed on myeloid cells 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qMmuCID0020213
List Price:    $125.00
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PrimePCR™ Probe Assay: Trem2, Mouse
Triggering receptor expressed on myeloid cells 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qMmuCEP0054571
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Trem2, Mouse
Triggering receptor expressed on myeloid cells 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dMmuEG5066316
Info:   EG; Same primer pair as used in qPCR assay qMmuCED0046145; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Trem2, Mouse
Triggering receptor expressed on myeloid cells 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dMmuEG5082398
Info:   EG; Same primer pair as used in qPCR assay qMmuCID0020213; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Trem2, Mouse
Triggering receptor expressed on myeloid cells 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dMmuCPE5096262
Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0054571; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: Trem2, Mouse
Triggering receptor expressed on myeloid cells 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dMmuCPE5096263
Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCEP0054571; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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