Gene:  TFE3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF TFE3 TFEB and TFEC. The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer. The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation. The TEF3 protein interacts with transcription regulators such as E2F3 SMAD3 and LEF-1 and is involved in TGF-beta-induced transcription playing important roles in cell growth proliferation and osteoclast and macrophage differentiation. The TFE3 protein also activates hepatic IRS-2 gene and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1); it participates in insulin signaling and could be a therapeutic target for diabetes. This gene is also involved in chromosomal translocations resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas such as PRCC-TFE3 RCC17-TFE3 PSF-TFE3 NonO (p54nrb)-TFE3 and ASPL-TFE3.[provided by RefSeq Dec 2009]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: TFE3, Human
transcription factor binding to IGHM enhancer 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006543
Info:   Same primer pair as used in probe assay qHsaCIP0026212
List Price:    $130.00
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PrimePCR™ Probe Assay: TFE3, Human
transcription factor binding to IGHM enhancer 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026212
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TFE3, Human
transcription factor binding to IGHM enhancer 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5014541
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0006543; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TFE3, Human
transcription factor binding to IGHM enhancer 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5046852
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026212; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TFE3, Human
transcription factor binding to IGHM enhancer 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5046853
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026212; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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