Gene:  TDP1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: TDP1, Human
tyrosyl-DNA phosphodiesterase 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011194
Info:   Same primer pair as used in probe assay qHsaCIP0027904
List Price:    $130.00
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PrimePCR™ Probe Assay: TDP1, Human
tyrosyl-DNA phosphodiesterase 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027904
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TDP1, Human
tyrosyl-DNA phosphodiesterase 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5017705
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0011194; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TDP1, Human
tyrosyl-DNA phosphodiesterase 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5049792
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027904; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TDP1, Human
tyrosyl-DNA phosphodiesterase 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5049793
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027904; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
Your Price:   Log In
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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