Gene:  TCEB2, Human

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This gene encodes the protein elongin B which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2 B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq Aug 2008]

PrimePCR™ SYBR® Green Assay: TCEB2, Human
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0038663
Info:   Same primer pair as used in probe assay qHsaCEP0041385
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PrimePCR™ Probe Assay: TCEB2, Human
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0041385
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