Gene:  TAB3, Human

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The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein and the similar and functionally redundant protein MAP3K7IP2/TAB2 forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described but their biological validity has not been determined. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: TAB3, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009986
Info:   Same primer pair as used in probe assay qHsaCIP0027413
List Price:    $138.00
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PrimePCR™ Probe Assay: TAB3, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027413
List Price:    $202.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TAB3, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5016759
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0009986; Intron-spanning
List Price:    $138.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TAB3, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5048920
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027413; Intron-spanning
 
Fluorophore:   FAM
List Price:    $207.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TAB3, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5048921
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027413; Intron-spanning
 
Fluorophore:   HEX
List Price:    $207.00
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PrimePCR™ ddPCR™ Mutation Assay:TAB3 p.M185V, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504012
Info:   70nt amplicon; exonic; in silico
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PrimePCR™ ddPCR™ Mutation Assay:TAB3 WT for p.M185V, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504013
Info:   70nt amplicon; exonic; in silico
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    Related pathways not available
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