Gene:  TAB1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1 which is known to mediate various intracellular signaling pathways such as those induced by TGF beta interleukin 1 and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1 while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha) and thus represents an alternative activation pathway in addition to the MAPKK pathways which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: TAB1, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017701
Info:   Same primer pair as used in probe assay qHsaCIP0031413
List Price:    $130.00
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PrimePCR™ Probe Assay: TAB1, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031413
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TAB1, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5022717
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017701; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TAB1, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5056000
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031413; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: TAB1, Human
TGF-beta activated kinase 1/MAP3K7 binding protein 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5056001
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031413; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
Your Price:   Log In
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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