Gene:  SPTBN2, Human

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Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2) is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to but distinct from the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia SCA5 that is characterized by neurodegeneration progressive locomotor incoordination dysarthria and uncoordinated eye movements. [provided by RefSeq Dec 2009]

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PrimePCR™ SYBR® Green Assay: SPTBN2, Human
spectrin, beta, non-erythrocytic 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047016
Info:   Same primer pair as used in probe assay qHsaCEP0054277
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: SPTBN2, Human
spectrin, beta, non-erythrocytic 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014829
Info:   Recommended - best coverage
List Price:    $125.00
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PrimePCR™ Probe Assay: SPTBN2, Human
spectrin, beta, non-erythrocytic 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054277
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SPTBN2, Human
spectrin, beta, non-erythrocytic 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5011391
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0047016; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SPTBN2, Human
spectrin, beta, non-erythrocytic 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5020344
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0014829; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SPTBN2, Human
spectrin, beta, non-erythrocytic 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5041092
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054277; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SPTBN2, Human
spectrin, beta, non-erythrocytic 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5041093
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054277; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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