Gene:  SORCS1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: SORCS1, Human
sortilin-related VPS10 domain containing receptor 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0022188
Info:   Same primer pair as used in probe assay qHsaCIP0033328
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PrimePCR™ Probe Assay: SORCS1, Human
sortilin-related VPS10 domain containing receptor 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0033328
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PrimePCR™ ddPCR™ Copy Number Assay: SORCS1, Human
sortilin-related VPS10 domain containing receptor 1

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000424
Info:   69nt amplicon; exonic
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:SORCS1 p.R1078*, Human
sortilin-related VPS10 domain containing receptor 1

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504130
Info:   65nt amplicon; exonic; in-silico
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:SORCS1 WT for p.R1078*, Human
sortilin-related VPS10 domain containing receptor 1

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504131
Info:   65nt amplicon; exonic; in-silico
 
Fluorophore:   HEX
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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