Gene:  SNCA, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Design and Validation of Real-Time PCR Primers
Pathway Curation
Control and Reference Assays for Real-Time PCR

Alpha-synuclein is a member of the synuclein family which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq Mar 2009]

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PrimePCR™ SYBR® Green Assay: SNCA, Human
synuclein, alpha (non A4 component of amyloid precursor)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003070
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PrimePCR™ SYBR® Green Assay: SNCA, Human
synuclein, alpha (non A4 component of amyloid precursor)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045260
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052521
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PrimePCR™ Probe Assay: SNCA, Human
synuclein, alpha (non A4 component of amyloid precursor)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052521
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PrimePCR™ ddPCR™ Copy Number Assay: SNCA, Human
synuclein, alpha (non A4 component of amyloid precursor)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000476
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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