Gene:  SLC8A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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In cardiac myocytes Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM Apr 2004]

PrimePCR™ SYBR® Green Assay: SLC8A1, Human
solute carrier family 8 (sodium/calcium exchanger), member 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047567
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0054827
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PrimePCR™ SYBR® Green Assay: SLC8A1, Human
solute carrier family 8 (sodium/calcium exchanger), member 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012332
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PrimePCR™ Probe Assay: SLC8A1, Human
solute carrier family 8 (sodium/calcium exchanger), member 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054827
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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