Gene:  SLC46A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia hypoimmunoglobulinemia and recurrent infections. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jun 2011]

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PrimePCR™ SYBR® Green Assay: SLC46A1, Human
solute carrier family 46 (folate transporter), member 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037938
Info:   Same primer pair as used in probe assay qHsaCEP0040661
List Price:    $130.00
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PrimePCR™ Probe Assay: SLC46A1, Human
solute carrier family 46 (folate transporter), member 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040661
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SLC46A1, Human
solute carrier family 46 (folate transporter), member 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5006330
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037938; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SLC46A1, Human
solute carrier family 46 (folate transporter), member 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5030972
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040661; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SLC46A1, Human
solute carrier family 46 (folate transporter), member 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5030973
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040661; exonic
 
Fluorophore:   HEX
List Price:    $195.00
Your Price:   Log In
Quantity:  
 
    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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