Gene:  SLC12A3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome a disease similar to Bartter's syndrome that is characterized by hypokalemic alkalosis combined with hypomagnesemia low urinary calcium and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: SLC12A3, Human
solute carrier family 12 (sodium/chloride transporters), member 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017314
Info:   Same primer pair as used in probe assay qHsaCIP0031156
List Price:    $130.00
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PrimePCR™ Probe Assay: SLC12A3, Human
solute carrier family 12 (sodium/chloride transporters), member 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031156
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SLC12A3, Human
solute carrier family 12 (sodium/chloride transporters), member 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5022415
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017314; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SLC12A3, Human
solute carrier family 12 (sodium/chloride transporters), member 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055536
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031156; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SLC12A3, Human
solute carrier family 12 (sodium/chloride transporters), member 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055537
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031156; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
Your Price:   Log In
Quantity:  
 
    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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