Gene:  SIGLEC12, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein upon tyrosine phosphorylation has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: SIGLEC12, Human
sialic acid binding Ig-like lectin 12

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037035
Info:   Same primer pair as used in probe assay qHsaCEP0039759
List Price:    $125.00
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PrimePCR™ Probe Assay: SIGLEC12, Human
sialic acid binding Ig-like lectin 12

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039759
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SIGLEC12, Human
sialic acid binding Ig-like lectin 12

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5006067
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037035; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SIGLEC12, Human
sialic acid binding Ig-like lectin 12

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5030446
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0039759; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: SIGLEC12, Human
sialic acid binding Ig-like lectin 12

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5030447
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0039759; exonic
 
Fluorophore:   HEX
List Price:    $190.00
Your Price:   Log In
Quantity:  
 
    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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