Gene:  SERPINC1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene many of which are known to cause antithrombin-III deficiency. [provided by RefSeq Jul 2009]

PrimePCR™ SYBR® Green Assay: SERPINC1, Human
serpin peptidase inhibitor, clade C (antithrombin), member 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043745
Info:   Same primer pair as used in probe assay qHsaCEP0051007
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PrimePCR™ SYBR® Green Assay: SERPINC1, Human
serpin peptidase inhibitor, clade C (antithrombin), member 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021147
Info:   Recommended - best coverage
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PrimePCR™ Probe Assay: SERPINC1, Human
serpin peptidase inhibitor, clade C (antithrombin), member 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051007
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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