Gene:  SDHB, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Complex II of the respiratory chain which is specifically involved in the oxidation of succinate carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: SDHB, Human
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043721
Info:   Same primer pair as used in probe assay qHsaCEP0050983
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PrimePCR™ SYBR® Green Assay: SDHB, Human
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011704
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PrimePCR™ Probe Assay: SDHB, Human
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050983
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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