Gene:  SCN3A, Human

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Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: SCN3A, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045599
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052860
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PrimePCR™ SYBR® Green Assay: SCN3A, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012289
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PrimePCR™ Probe Assay: SCN3A, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052860
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PrimePCR™ ddPCR™ Copy Number Assay: SCN3A, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000538
Info:   70nt amplicon; crosses exon-intron junction
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:SCN3A p.R378R, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501242
Info:   100nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:SCN3A WT for p.R378R, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501243
Info:   100nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay:SCN3A p.V1432A, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2506184
Info:   100nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Mutation Assay:SCN3A WT for p.V1432A, Human
sodium channel, voltage-gated, type III, alpha subunit

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2506185
Info:   100nt amplicon; crosses exon-intron junction; in-silico
 
Fluorophore:   HEX
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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