Gene:  RP1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein another retinal-specific protein play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Transcript variants resulted from an alternative promoter and alternative splicings have been found which overlap the current reference sequence and has several exons upstream and downstream of the current reference sequence. However the biological validity and full-length nature of some variants cannot be determined at this time.[provided by RefSeq Sep 2010]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042998
Info:   Same primer pair as used in probe assay qHsaCEP0050260
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017951
List Price:    $125.00
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PrimePCR™ Probe Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050260
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5007826
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042998; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5022900
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017951; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5033964
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0050260; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: RP1, Human
retinitis pigmentosa 1 (autosomal dominant)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5033965
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050260; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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