Gene:  RNF139, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL as well as with COPS5/JAB1 a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: RNF139, Human
ring finger protein 139

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0034629
Info:   Same primer pair as used in probe assay qHsaCEP0035454
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PrimePCR™ Probe Assay: RNF139, Human
ring finger protein 139

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0035454
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PrimePCR™ ddPCR™ Copy Number Assay: RNF139, Human
ring finger protein 139

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2500458
Info:   59nt amplicon; exonic
 
Fluorophore:   FAM
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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