Gene:  RBL1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: RBL1, Human
retinoblastoma-like 1 (p107)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014916
Info:   Same primer pair as used in probe assay qHsaCIP0029610
List Price:    $130.00
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PrimePCR™ Probe Assay: RBL1, Human
retinoblastoma-like 1 (p107)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029610
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RBL1, Human
retinoblastoma-like 1 (p107)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5020400
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0014916; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: RBL1, Human
retinoblastoma-like 1 (p107)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5052632
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029610; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: RBL1, Human
retinoblastoma-like 1 (p107)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5052633
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029610; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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