Gene:  RANBP2, Human

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RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that for some substrates modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: RANBP2, Human
RAN binding protein 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045595
Info:   Same primer pair as used in probe assay qHsaCEP0052856
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: RANBP2, Human
RAN binding protein 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013280
Info:   Recommended - best coverage
List Price:    $125.00
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PrimePCR™ Probe Assay: RANBP2, Human
RAN binding protein 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052856
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RANBP2, Human
RAN binding protein 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5010109
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0045595; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: RANBP2, Human
RAN binding protein 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5019219
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0013280; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: RANBP2, Human
RAN binding protein 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5038528
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052856; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: RANBP2, Human
RAN binding protein 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5038529
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052856; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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