Gene:  PTPRB, Human

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP contains an extracellular domain a single transmembrane segment and one intracytoplasmic catalytic domain thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats which was shown to interact with neuronal receptor and cell adhesion molecules such as contactin and tenascin C. This protein was also found to interact with sodium channels and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion neurite growth and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq May 2011]

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PrimePCR™ SYBR® Green Assay: PTPRB, Human
protein tyrosine phosphatase, receptor type, B

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044179
Info:   Same primer pair as used in probe assay qHsaCEP0051441
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: PTPRB, Human
protein tyrosine phosphatase, receptor type, B

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009577
List Price:    $125.00
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PrimePCR™ Probe Assay: PTPRB, Human
protein tyrosine phosphatase, receptor type, B

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051441
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PTPRB, Human
protein tyrosine phosphatase, receptor type, B

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5008863
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0044179; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PTPRB, Human
protein tyrosine phosphatase, receptor type, B

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5016489
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0009577; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PTPRB, Human
protein tyrosine phosphatase, receptor type, B

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5036038
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051441; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PTPRB, Human
protein tyrosine phosphatase, receptor type, B

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5036039
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051441; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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