Gene:  PNMA1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The PNMA1 gene encodes an antineuronal antibody (anti-Ma) present in patients with paraneoplastic neurologic disorders (Dalmau et al. 1999 [PubMed 10050892]). Some paraneoplastic syndromes affecting the nervous system are associated with antibodies that react with neuronal proteins and the causal tumor (onconeuronal antigens) (summarized by Dalmau et al. 1999 [PubMed 10050892]). Several of these antibodies are markers of specific neurologic syndromes associated with distinct types of cancer. The presence of some antibodies is so specific that disorders previously identified by brain biopsy or at autopsy can be diagnosed serologically. The expression of neuronal proteins by the tumor appears to be a crucial step that breaks the immune tolerance for otherwise normal neuronal proteins. The identity of most onconeuronal antigens was established by probing human cDNA expression libraries with serum containing antineuronal antibodies.[supplied by OMIM May 2010]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: PNMA1, Human
paraneoplastic antigen MA1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0018854
Info:   Same primer pair as used in probe assay qHsaCEP0032055
List Price:    $125.00
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PrimePCR™ Probe Assay: PNMA1, Human
paraneoplastic antigen MA1

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0032055
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PNMA1, Human
paraneoplastic antigen MA1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5003982
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0018854; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PNMA1, Human
paraneoplastic antigen MA1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5028248
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0032055; Exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PNMA1, Human
paraneoplastic antigen MA1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5028249
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0032055; Exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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