Gene:  PLAGL1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties and thus thought to function as a tumor suppressor. In addition overexpression of this gene during fetal development is believed to underlie the rare disorder transient neonatal diabetes mellitus (TNDM). This gene is imprinted with preferential expression of the paternal allele in many tissues however biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms have been found for this gene. [provided by RefSeq Oct 2010]

PrimePCR™ SYBR® Green Assay: PLAGL1, Human
pleiomorphic adenoma gene-like 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036455
Info:   Same primer pair as used in probe assay qHsaCEP0039179
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PrimePCR™ Probe Assay: PLAGL1, Human
pleiomorphic adenoma gene-like 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039179
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
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LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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