Gene:  PKD1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also six pseudogenes closely linked in a known duplicated region on chromosome 16p have been described. [provided by RefSeq Oct 2008]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: PKD1, Human
polycystic kidney disease 1 (autosomal dominant)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002126
Info:   Recommended - best coverage
List Price:    $130.00
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PrimePCR™ SYBR® Green Assay: PKD1, Human
polycystic kidney disease 1 (autosomal dominant)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0041951
Info:   Same primer pair as used in probe assay qHsaCEP0049214
List Price:    $130.00
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Add to Custom Plate
PrimePCR™ Probe Assay: PKD1, Human
polycystic kidney disease 1 (autosomal dominant)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049214
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PKD1, Human
polycystic kidney disease 1 (autosomal dominant)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5000901
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002126; Exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PKD1, Human
polycystic kidney disease 1 (autosomal dominant)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5189014
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0041951; exonic
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PKD1, Human
polycystic kidney disease 1 (autosomal dominant)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191719
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049214; exonic
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PKD1, Human
polycystic kidney disease 1 (autosomal dominant)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5191720
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049214; exonic
 
Fluorophore:   HEX
List Price:    $195.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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