Gene:  PEX5, Human

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The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD) a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Oct 2008]

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PrimePCR™ SYBR® Green Assay: PEX5, Human
peroxisomal biogenesis factor 5

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044895
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052157
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: PEX5, Human
peroxisomal biogenesis factor 5

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012304
List Price:    $125.00
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PrimePCR™ Probe Assay: PEX5, Human
peroxisomal biogenesis factor 5

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052157
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PEX5, Human
peroxisomal biogenesis factor 5

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5009499
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0044895; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PEX5, Human
peroxisomal biogenesis factor 5

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5018543
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0012304; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PEX5, Human
peroxisomal biogenesis factor 5

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037310
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052157; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PEX5, Human
peroxisomal biogenesis factor 5

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5037311
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052157; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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