Gene:  PDP1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Pyruvate dehydrogenase (E1) is one of the three components (E1 E2 and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit encoded by this gene is the former and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq Jun 2009]

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PrimePCR™ SYBR® Green Assay: PDP1, Human
pyruvate dehyrogenase phosphatase catalytic subunit 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002598
Info:   Same primer pair as used in probe assay qHsaCEP0024439
List Price:    $125.00
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PrimePCR™ Probe Assay: PDP1, Human
pyruvate dehyrogenase phosphatase catalytic subunit 1

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024439
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PDP1, Human
pyruvate dehyrogenase phosphatase catalytic subunit 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5001276
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002598; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PDP1, Human
pyruvate dehyrogenase phosphatase catalytic subunit 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5026138
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0024439; Exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PDP1, Human
pyruvate dehyrogenase phosphatase catalytic subunit 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5026139
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0024439; Exonic
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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