Gene:  PCBP1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA human Papillomavirus type 16 L2 mRNA and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: PCBP1, Human
poly(rC) binding protein 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0056788
Info:   Same primer pair as used in probe assay qHsaCEP0057893
List Price:    $125.00
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PrimePCR™ Probe Assay: PCBP1, Human
poly(rC) binding protein 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0057893
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PCBP1, Human
poly(rC) binding protein 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5013427
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056788; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PCBP1, Human
poly(rC) binding protein 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5045164
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0057893; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PCBP1, Human
poly(rC) binding protein 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5045165
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0057893; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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