Gene:  PARK2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The precise function of this gene is unknown; however the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: PARK2, Human
parkinson protein 2, E3 ubiquitin protein ligase (parkin)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0036905
Info:   Same primer pair as used in probe assay qHsaCIP0039629
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PrimePCR™ Probe Assay: PARK2, Human
parkinson protein 2, E3 ubiquitin protein ligase (parkin)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0039629
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PARK2, Human
parkinson protein 2, E3 ubiquitin protein ligase (parkin)

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5025038
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0036905; Intron-spanning
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PrimePCR™ ddPCR™ Copy Number Assay: PARK2, Human
parkinson protein 2, E3 ubiquitin protein ligase (parkin)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000046
Info:   FAM: 70nt amplicon; intronic
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Copy Number Assay: PARK2, Human
parkinson protein 2, E3 ubiquitin protein ligase (parkin)

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2507131
Info:   HEX; 70nt amplicon; intronic; HEX version of PARK2 (dHsaCP1000046)
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Expression Probe Assay: PARK2, Human
parkinson protein 2, E3 ubiquitin protein ligase (parkin)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5058762
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0039629; Intron-spanning
 
Fluorophore:   FAM
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PrimePCR™ ddPCR™ Expression Probe Assay: PARK2, Human
parkinson protein 2, E3 ubiquitin protein ligase (parkin)

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5058763
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0039629; Intron-spanning
 
Fluorophore:   HEX
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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