Gene:  PAK6, Human

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This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes including cytoskeleton rearrangement apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR) which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: PAK6, Human
p21 protein (Cdc42/Rac)-activated kinase 6

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014240
Info:   Same primer pair as used in probe assay qHsaCIP0029277
List Price:    $125.00
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PrimePCR™ Probe Assay: PAK6, Human
p21 protein (Cdc42/Rac)-activated kinase 6

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029277
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PAK6, Human
p21 protein (Cdc42/Rac)-activated kinase 6

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5019928
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0014240; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PAK6, Human
p21 protein (Cdc42/Rac)-activated kinase 6

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5052076
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029277; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: PAK6, Human
p21 protein (Cdc42/Rac)-activated kinase 6

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5052077
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029277; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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