Gene:  NRG3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation migration differentiation and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor ERBB4 and is thought to influence neuroblast proliferation migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq Sep 2009]

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PrimePCR™ SYBR® Green Assay: NRG3, Human
neuregulin 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0007944
Info:   Same primer pair as used in probe assay qHsaCIP0026577
List Price:    $125.00
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PrimePCR™ Probe Assay: NRG3, Human
neuregulin 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026577
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NRG3, Human
neuregulin 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5015259
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0007944; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: NRG3, Human
neuregulin 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047490
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026577; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: NRG3, Human
neuregulin 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047491
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026577; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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