Gene:  NR1I2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene product belongs to the nuclear receptor superfamily members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4 binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4 including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms some of which use non-AUG (CUG) translation initiation codon have been described for this gene. Additional transcript variants exist however they have not been fully characterized. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: NR1I2, Human
nuclear receptor subfamily 1, group I, member 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045230
Info:   Recommended - best efficiency; Same primer pair as used in probe assay qHsaCEP0052491
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PrimePCR™ SYBR® Green Assay: NR1I2, Human
nuclear receptor subfamily 1, group I, member 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021390
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PrimePCR™ Probe Assay: NR1I2, Human
nuclear receptor subfamily 1, group I, member 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052491
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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