Gene:  NR0B2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family a group of transcription factors regulated by small hydrophobic hormones a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors inhibiting their ligand-dependent transcriptional activation. In addition interaction with estrogen receptors has been demonstrated leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: NR0B2, Human
nuclear receptor subfamily 0, group B, member 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044415
Info:   Same primer pair as used in probe assay qHsaCEP0051677
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PrimePCR™ SYBR® Green Assay: NR0B2, Human
nuclear receptor subfamily 0, group B, member 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014043
Info:   Recommended - best negative control
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PrimePCR™ Probe Assay: NR0B2, Human
nuclear receptor subfamily 0, group B, member 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051677
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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