Gene:  NPC1, Human

print
PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

Why PrimePCR?

PrimePCR
Lookup Tool
Design and Validation of Real-Time PCR Primers
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq Aug 2009]

Select a product type :   All   qPCR   ddPCR
PrimePCR™ SYBR® Green Assay: NPC1, Human
NPC1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017572
Info:   Same primer pair as used in probe assay qHsaCIP0031331
List Price:    $125.00
Your Price:   Log In
Quantity:  
 
Add to Custom Plate
PrimePCR™ Probe Assay: NPC1, Human
NPC1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0031331
List Price:    $180.00
Your Price:   Log In
Quantity:  
 
PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NPC1, Human
NPC1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5022618
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0017572; Intron-spanning
List Price:    $125.00
Your Price:   Log In
Quantity:  
 
PrimePCR™ ddPCR™ Expression Probe Assay: NPC1, Human
NPC1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055856
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031331; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
Your Price:   Log In
Quantity:  
 
PrimePCR™ ddPCR™ Expression Probe Assay: NPC1, Human
NPC1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5055857
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031331; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
Your Price:   Log In
Quantity:  
 
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
Get Help

Call us at 1-800-4-BIORAD (1-800-424-6723)

Sign Up for Bio-Rad Updates!
Enter your email address below to receive your choice of the latest news, promotions, and more.