Gene:  NCSTN, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a Type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins including Notch receptors and beta-amyloid precursor protein and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Alternatively spliced transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: NCSTN, Human
nicastrin

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012336
Info:   Same primer pair as used in probe assay qHsaCIP0028400
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PrimePCR™ Probe Assay: NCSTN, Human
nicastrin

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028400
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PrimePCR™ ddPCR™ Copy Number Assay: NCSTN, Human
nicastrin

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000228
 
Fluorophore:   FAM
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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