Gene:  Myc, Mouse

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a multifunctional nuclear phosphoprotein that plays a role in cell cycle progression apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations overexpression rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors leukemias and lymphomas including Burkitt lymphoma in human. There is evidence to show that alternative translation initiations from an upstream in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini in human and mouse. Under conditions of stress such as high cell densities and methionine deprivation there is a specific and dramatic increase in the synthesis of the non-AUG initiated protein suggesting its importance in times of adversity. Alternative splicing results in multiple transcript variants. [provided by RefSeq Apr 2010]

PrimePCR™ SYBR® Green Assay: Myc, Mouse
Myelocytomatosis oncogene

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qMmuCID0006528
Info:   Same primer pair as used in probe assay qMmuCIP0028153
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PrimePCR™ Probe Assay: Myc, Mouse
Myelocytomatosis oncogene

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qMmuCIP0028153
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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