Gene:  MMP25, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

Why PrimePCR?

PrimePCR
Lookup Tool
Design and Validation of Real-Time PCR Primers-test
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation the encoded protein is thought to inactivate alpha-1 proteinase inhibitor a major tissue protectant against proteolytic enzymes released by activated neutrophils facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: MMP25, Cow
Matrix metallopeptidase 25

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qBtaCED0014879
List Price:    $105.00
Your Price:   Log In
Quantity:  
 
Add to Custom Plate
PrimePCR™ Probe Assay: MMP25, Cow
Matrix metallopeptidase 25

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qBtaCEP0034641
List Price:    $202.00
Your Price:   Log In
Quantity:  
 
    Related pathways not available
Number Description Download