Gene:  LPIN3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Humans lipodystrophy is characterized by loss of body fat fatty liver hypertriglyceridemia and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1 LPIN2 and LPIN3). Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12 respectively. The mouse genes encoding Lpin1 Lpin2 and Lpin3 mapped to chromosome 12 17 and 2 respectively. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: LPIN3, Human
lipin 3

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0004591
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: LPIN3, Human
lipin 3

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044469
Info:   Same primer pair as used in probe assay qHsaCEP0051731
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: LPIN3, Human
lipin 3

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051731
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: LPIN3, Human
lipin 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5002778
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0004591; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: LPIN3, Human
lipin 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5009116
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0044469; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: LPIN3, Human
lipin 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5036544
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0051731; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: LPIN3, Human
lipin 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5036545
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051731; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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