Gene:  LDB2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Genes encoding LIM domain-binding factors were initially isolated in a screen for proteins that physically interact with the LIM domains of nuclear proteins (summarized by Semina et al. 1998 [PubMed 9799849]). These proteins such as the one encoded by the LDB2 gene are capable of binding to a variety of transcription factors and are likely to function at enhancers to bring together diverse transcription factors and form higher order activation complexes or to block formation of such complexes (Jurata and Gill 1997 [PubMed 9315627]). The family of genes encoding LIM domain-binding factors includes 2 members isolated from the mouse Clim1 (Bach et al. 1997 [PubMed 9192866]) and Clim2/Lbd1/Nli (Agulnick et al. 1996 [PubMed 8918878]; Jurata et al. 1996 [PubMed 8876198]; Bach et al. 1997 [PubMed 9192866]) and their homologs cloned from the frog chicken and fly. The fact that LIM domain-binding factors are likely to be involved in the coordination of the transcriptional activity of many diverse factors might implicate them in human phenotypes characterized by multiple affected sites.[supplied by OMIM Jul 2010]

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PrimePCR™ SYBR® Green Assay: LDB2, Human
LIM domain binding 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010761
Info:   Same primer pair as used in probe assay qHsaCIP0027720
List Price:    $125.00
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PrimePCR™ Probe Assay: LDB2, Human
LIM domain binding 2

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027720
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: LDB2, Human
LIM domain binding 2

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5017365
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0010761; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: LDB2, Human
LIM domain binding 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5049468
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027720; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: LDB2, Human
LIM domain binding 2

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5049469
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027720; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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