Gene:  KCNQ1, Human

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This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome) Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. This gene exhibits tissue-specific imprinting with preferential expression from the maternal allele in some tissues and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS) and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Aug 2011]

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PrimePCR™ SYBR® Green Assay: KCNQ1, Human
potassium voltage-gated channel, KQT-like subfamily, member 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0007481
Info:   Same primer pair as used in probe assay qHsaCIP0026485
List Price:    $130.00
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PrimePCR™ Probe Assay: KCNQ1, Human
potassium voltage-gated channel, KQT-like subfamily, member 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026485
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: KCNQ1, Human
potassium voltage-gated channel, KQT-like subfamily, member 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5015119
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0007481; Intron-spanning
List Price:    $130.00
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PrimePCR™ ddPCR™ Expression Probe Assay: KCNQ1, Human
potassium voltage-gated channel, KQT-like subfamily, member 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047332
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026485; Intron-spanning
 
Fluorophore:   FAM
List Price:    $195.00
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PrimePCR™ ddPCR™ Expression Probe Assay: KCNQ1, Human
potassium voltage-gated channel, KQT-like subfamily, member 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047333
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026485; Intron-spanning
 
Fluorophore:   HEX
List Price:    $195.00
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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