Gene:  KCNN3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Feb 2011]

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PrimePCR™ SYBR® Green Assay: KCNN3, Human
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0007374
Info:   Same primer pair as used in probe assay qHsaCIP0026444
List Price:    $125.00
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PrimePCR™ Probe Assay: KCNN3, Human
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026444
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: KCNN3, Human
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5015039
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0007374; Intron-spanning
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression Probe Assay: KCNN3, Human
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047260
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0026444; Intron-spanning
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: KCNN3, Human
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5047261
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0026444; Intron-spanning
 
Fluorophore:   HEX
List Price:    $190.00
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    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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