Gene:  IDO1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes indoleamine 23-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan L-tryptophan 5-hydroxy-tryptophan tryptamine and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense neuropathology immunoregulation and antioxidant activity. Through its expression in dendritic cells monocytes and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq Feb 2011]

PrimePCR™ SYBR® Green Assay: IDO1, Human
indoleamine 2,3-dioxygenase 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044371
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0051633
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PrimePCR™ SYBR® Green Assay: IDO1, Human
indoleamine 2,3-dioxygenase 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0008875
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PrimePCR™ Probe Assay: IDO1, Human
indoleamine 2,3-dioxygenase 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051633
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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