Gene:  HSPG2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes the perlecan protein which consists of a core protein to which three long chains of glycosaminoglycans (heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin prolargin collagen type IV FGFBP1 FBLN2 FGF7 and Transthyretin etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g. FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1 Silverman-Handmaker type of dyssegmental dysplasia and Tardive dyskinesia.[provided by RefSeq Mar 2010]

PrimePCR™ SYBR® Green Assay: HSPG2, Human
heparan sulfate proteoglycan 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036599
Info:   Same primer pair as used in probe assay qHsaCEP0039323
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PrimePCR™ Probe Assay: HSPG2, Human
heparan sulfate proteoglycan 2

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039323
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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