Gene:  HRK, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain but not with the death-promoting BCL2-related proteins BAX BAK or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: HRK, Human
harakiri, BCL2 interacting protein (contains only BH3 domain)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036554
Info:   Same primer pair as used in probe assay qHsaCEP0039278
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PrimePCR™ Probe Assay: HRK, Human
harakiri, BCL2 interacting protein (contains only BH3 domain)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039278
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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