Gene:  GRM8, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology putative signal transduction mechanisms and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4 GRM6 GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

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PrimePCR™ SYBR® Green Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002454
List Price:    $125.00
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PrimePCR™ SYBR® Green Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047372
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0054632
List Price:    $125.00
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Add to Custom Plate
PrimePCR™ Probe Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054632
List Price:    $180.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5001162
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002454; Exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5011717
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0047372; exonic
List Price:    $125.00
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PrimePCR™ ddPCR™ Copy Number Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2500281
Info:   FAM; 70nt amplicon; exonic; FAM version of GRM8 (dHsaCP2506458)
 
Fluorophore:   FAM
List Price:    $230.00
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PrimePCR™ ddPCR™ Copy Number Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506458
Info:   HEX; 70nt amplicon; exonic; HEX version of GRM8 (dHsaCP2500281)
 
Fluorophore:   HEX
List Price:    $230.00
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PrimePCR™ ddPCR™ Expression Probe Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5041744
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054632; exonic
 
Fluorophore:   FAM
List Price:    $190.00
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PrimePCR™ ddPCR™ Expression Probe Assay: GRM8, Human
glutamate receptor, metabotropic 8

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5041745
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054632; exonic
 
Fluorophore:   HEX
List Price:    $190.00
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Quantity:  
 
    Related pathways not available
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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